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Two basic image-editing tools are the Pen tool and the Brush tool. The former has a multitude of shapes (called selection tools), including dotted-line and cross-hatching shapes that help you edit images in a realistic way. In addition, you can use the Pen tool to create selections, and you can draw paths with it. The Brush tool, on the other hand, enables you to apply brush strokes to a selection or an image. You can apply different brush sizes, colors, strokes, and textures to brush up a logo, a poster, or a background. In this chapter, I give you a quick tutorial on how to use Photoshop to create a simple watermark image, one of the most common time-saving tasks in the world of graphic design. Let’s create a watermark that can be easily printed on business cards, brochures, or other promotional materials. Mastering the Photoshop Watermark A watermark is a graphic pattern that can be printed on business cards, advertisements, posters, or promotional materials, such as envelopes and paper-goods packaging. A watermark is not much different from a stamp and is commonly used as a design component in creating and optimizing print projects. Because the watermark may be printed on ordinary paper stock, you need to be careful that the watermark isn’t apparent and that it doesn’t appear to be part of the photo, or be grouped as an object instead of a background layer. In the following exercise, you create a watermark that gets printed on ordinary business cards. 01 Create a new Photoshop document, 150 × 300 pixels, and choose Photoshop, and Normal, as the default setting. 02 Create a new layer, and with the Pen tool, draw a path that forms a zigzag pattern and creates a wavy look. Leave the stroke color at black, and set the width to 14 pixels. When you’re done, right-click the selected area, and choose Edit Contents, as shown in Figure 5-1. Figure 5-1: To create a watermark, make sure that the layer you create is locked, so that you can add text to it later on. 03 Add the Text tool from the Tools panel. Choose Text from the menu bar, and draw a small text box at the top-left corner of the canvas area. Start typing your company name or other text, and select the From Photoshop option, as

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More importantly, Photoshop Elements lets you save files as a.psd file, an image editor’s industry standard file format. Learn how to use Photoshop Elements for retouching, changing photo color, and more. How to Edit Photo Files in Photoshop Elements This guide provides a comprehensive step-by-step tutorial for the beginner, intermediate and advanced Photoshop Elements user. Whether you’re editing RAW files or working with JPEGs, a variety of Photoshop Elements commands let you do the following: Create a new Photoshop Elements document, edit an existing image, and zoom in on specific areas of a photo Edit JPEG photos — fill and convert image colors, sharpen or soften images Edit RAW files — delete, crop, enhance, delete shadows, fix lens issues, adjust white balance, etc. Apply and edit artistic effects, such as skin smoothing Adjust camera noise reduction and other digital noise reduction Add text and customize other layer settings Properly preparing your image can make the difference between a properly exposed, good looking photo and an over- or under-exposed, dark image. A few carefully selected settings can turn a useless (or even a good) photo into a stunning masterpiece. Print your photo, make it into a personal greeting card, and more using editing techniques Photoshop Elements has many built-in editing tools that are commonly used in professional digital photography. Most of these same tools are also available in the Advanced Editing panel of Photoshop. The interface of Photoshop Elements is very similar to that of Photoshop so it can be easy to learn the basics if you already have some experience with Photoshop. What To Know Before Working in Photoshop Elements If you know your way around a photo editor, Photoshop Elements may be a great tool for editing your photos and making them look even better than they did when you took them. Some of the editing tools have additional settings that allow you to adapt the look of your photos to your preferences, such as brightness, contrast, and sharpness. It is important to learn how to use Photoshop Elements to get the most out of the professional tools and the filter effects available in this free software. Before working with Photoshop Elements, you need to do the following: Find a quality source of images for editing. A selection of images from your camera or from websites and online stores is a good starting point. Create a new Photoshop Elements document. 388ed7b0c7

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A new method to validate a non-invasive transcutaneous bilirubinometer-based method for total serum bilirubin measurement in term neonates. To evaluate a new approach for transcutaneous bilirubin (TcB) analysis in clinical practice by a modification of the UBRITB 10 Plus UV Bilirubinometer. A prospective study was performed to develop an in-house method for TcB analysis. A group of 26 term neonates was studied. All measurements were performed by the UBRITB 10 Plus UV Bilirubinometer. The relationship between the in-house TcB and direct (DCB) and total serum bilirubin (TSB) measurements was explored. The TcB/TSB ratio was 2.8 ± 0.5. Using the median TcB of 25 µmol/L, the mean TcB/TSB ratio was 0.93 ± 0.19. The best fit-line equation for the DCB/TSB pair was: y = 0.78x + 0.6 (r2 = 0.91). The new approach provided a reliable method to measure TcB in term neonates. In the future, prospective studies are necessary to evaluate this new approach in comparison to other methods.1. Field of the Invention The present invention relates to a method for fabricating a semiconductor device, and more particularly, to a method for fabricating a semiconductor device that facilitates a planarization of an uppermost surface of a contact plug. 2. Description of the Prior Art A semiconductor device is manufactured by dividing a substrate into a plurality of semiconductor chips via a sawing process, and then each of the semiconductor chips is packaged. During an operation of the semiconductor device, an electrical contact is formed between metal layers disposed on an upper portion of the semiconductor chip and the substrate. Therefore, an insulating layer or a diffusion region is formed in a lower portion of the semiconductor chip to be in contact with the substrate. Generally, the diffusion region is formed in order to reduce a contact resistance. A conductive substance is filled in an upper portion of the insulating layer to be in contact with the metal layer. Then, the metal layer and the conductive substance are planarized to expose the surface of the insulating layer. The exposed insulating layer is defined as a contact plug. As described above, the conventional

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The overall objective of this project is the optimization and elaboration of the use of the multiphoton microscope (MPM) in measuring high spatio-temporal resolution Ca2+, and pH levels in neural tissue and cells, in vitro. Experiments will focus on: (1) measuring both 2-photon Ca2+ and 4-photon Ca2+ fluorescence, and calibrating these measurements against TPA-stimulated Ca2+ responses; (2) the depth profile of pH along mouse nerve fibers, by measuring changes in 2-photon fluorescence of a pH-sensitive dye; (3) monitoring graded increases in intracellular Ca2+ and pH in central neurons that exhibit regenerative axonal growth; (4) observing and quantifying motor neuron growth cone depolarization, in response to primary afferents that are rapidly stimulated during chronic nerve block.Retinoid X receptor alpha (RXRA) is selectively expressed in the developing nervous system and inhibits transcription of the paired-like homeodomain transcription factor Barx2. Retinoid receptors play important roles in the embryogenesis of the nervous system. It has been established that both the RA and RAR genes are involved in the development of the nervous system, but the exact function of retinoid receptors in the early embryogenesis and differentiation of the nervous system is still elusive. We reported previously that expression of a homeodomain transcription factor Barx2, an RA target gene, was induced during the differentiation of PC12 cells into neurons and regulated neuronal cell-specific expression of N-acetyltransferase (NAT) and dopamine-beta-hydroxylase (DBH). The present study demonstrates that the expression pattern of the retinoid X receptor alpha (RXRA) gene in the developing embryo is closely matched with that of Barx2. RXRA is selectively expressed in the spinal cord, hindbrain and forebrain, where Barx2 is also expressed, from day 6.5 to day 9.5 in mouse embryos. RXRA mRNA level during the period 6.5-8.5 correlates with that of Barx2 (rho = 0.90). RXRA mRNA expression gradually decreased in these regions after embryonic day 8.5, but it remained unaffected in the retinal cell layer. RXRA protein is expressed in the similar regions where Barx2 is expressed and co-localizes with Barx2 protein in the cell nucleus. Gel shift and ChIP ass

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